St. Gregory the Great Catholic Church is in unincorporated Beaufort County, but it hopes to seek annexation into Bluffton. The property has a Bluffton address but is not in town limits. Church officials have made an annexation request to the Town of Bluffton. The property is located on U.S. 278 between the Buckwalter Parkway intersection and Bluffton Township Fire District Station 35.
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